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Article

IL-2 and IL-4 polymorphisms as candidate genes in schizophrenia.

European archives of psychiatry and clinical neuroscience - 1 Mar 2006

Schwarz Markus J, Krönig Holger, Riedel Michael, Dehning Sandra, Douhet Anette, Spellmann Ilja, Ackenheil Manfred, Möller Hans-Jürgen, Müller Norbert

Abstract excerpt

An immune process, characterized by a relative predominance of the T helper-2 (Th2) system and possibly induced by a viral infection,may be involved in the pathophysiology of schizophrenia. In this context, functional polymorphisms in the Interleukin-2 (IL-2) and Interleukin-4 (IL-4) genes appear to be principal candidates for genetic schizophrenia research. Further evidence for these candidate genes comes from...

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PMID: 16091861
DOI: 10.1007/s00406-005-0603-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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