Article
Two novel biallelic polymorphisms in the IL-2 gene.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Dec 1998
John S, Turner D, Donn R, Sinnott P, Worthington J, Ollier W E, Hutchinson I V, Hajeer A H
Abstract excerpt
We have detected two novel single nucleotide polymorphisms in the IL-2 gene, at positions -330 and +166 relative to the transcription start site. The +166 change occurs within the leader peptide and does not affect amino acid sequence. The -330 polymorphism has two common alleles, making it an id...
Topics
- 5' Untranslated Regions
- Alleles
- Genotype
- Humans
- Interleukin-2
- Molecular Sequence Data
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length