Article
Recombination drives the evolution of GC-content in the human genome.
Molecular biology and evolution - 1 Jun 2004
Meunier Julien, Duret Laurent
Abstract excerpt
Unraveling the evolutionary forces responsible for variations of neutral substitution patterns among taxa or along genomes is a major issue in the identification of functional sequence features. Mammalian genomes show large-scale regional variations of GC-content (the isochores), but the substitution processes at the origin of this structure are poorly understood. We have analyzed the pattern of neutral...
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