Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effect of ABCA1 gene polymorphisms on ischaemic stroke risk and relationship with lipid profile.

BMC medical genetics - 6 Jun 2007

Pasdar Alireza, Yadegarfar Ghasem, Cumming Alastair, Whalley Lawrence, St Clair David, MacLeod Mary-Joan

Abstract excerpt

BACKGROUND: Ischaemic stroke is a common disorder with genetic and environmental components contributing to overall risk. Atherothromboembolic abnormalities, which play a crucial role in the pathogenesis of ischaemic stroke, are often the end result of dysregulation of lipid metabolism. The ATP Binding Cassette Transporter (ABCA1) is a key gene involved in lipid metabolism. It encodes the cholesterol regulatory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter 1
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Brain Ischemia

Share to Gene Frequency

Share to Genetic Markers

Share to Haplotypes

Share to Lipids

Share to Stroke

Source

Open in PubMed Open full text

Identifiers

PMID: 17553166
DOI: 10.1186/1471-2350-8-30
PMCID: PMC1894956

Genes

ABCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effect of ABCA1 gene polymorphisms on ischaemic stroke risk and relationship with lipid profile.PMID 17553166Read ↗

Genetic variations in ABCA1/G1 associated with plasma lipid levels and risk of ischemic stroke.Semantic proximity Read ↗

ABCA1 gene polymorphisms and their associations with coronary artery disease and plasma lipids in males from three ethnic populations in Singapore.Semantic proximity Read ↗

In-depth haplotype analysis of ABCA1 gene polymorphisms in relation to plasma ApoA1 levels and myocardial infarction.Semantic proximity Read ↗

Paraoxonase gene polymorphisms and haplotype analysis in a stroke population.Semantic proximity Read ↗

Association of ATP-Binding Cassette Transporter G1 Polymorphisms with Risk of Ischemic Stroke in the Chinese Han Population.Semantic proximity Read ↗

Decreased frequencies of ABCA1 polymorphisms R219K and V771M in Hungarian patients with cerebrovascular and cardiovascular diseases.Semantic proximity Read ↗

DNA Methylation and SNPs of ABCA1 Gene Promoter Affect Gene Expression and Involve in the Pathological Mechanism of Ischemic StrokeSemantic proximity Read ↗

A novel haplotype in ABCA1 gene effects plasma HDL-C concentration.Semantic proximity Read ↗

Chromosome 9p21 and ABCA1 Genetic Variants and Their Interactions on Coronary Heart Disease and Ischemic Stroke in a Chinese Han Population.Semantic proximity Read ↗

Genetic variation in ABCA1 predicts ischemic heart disease in the general population.Semantic proximity Read ↗

Common genetic variation in the ATP-binding cassette transporter A1, plasma lipids, and risk of coronary heart disease.Semantic proximity Read ↗

Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.