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Article

ABCA1 gene polymorphisms and their associations with coronary artery disease and plasma lipids in males from three ethnic populations in Singapore.

Human genetics - 1 Jul 2003

Tan Jenny Hui-Hui, Low Poh-Sim, Tan Yong-Seng, Tong Ming-Chuan, Saha Nilmani, Yang Hongyuan, Heng Chew-Kiat

Abstract excerpt

Mutations in the ATP-binding cassette transporter ABCA1 underlie Tangier disease and familial hypoalphaliproteinemia (FHA), disorders that are characterised by reduced high-density lipoprotein-cholesterol (HDL-C) concentration and cholesterol efflux, and increased coronary artery disease (CAD). We explored if polymorphisms in the ABCA1 gene are associated with CAD and variations in plasma lipid levels, especially...

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Source

Identifiers

PMID: 12709788
DOI: 10.1007/s00439-003-0943-3

Genes

ABCA1
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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