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Article

Effect of ABCA1 mutations on risk for myocardial infarction.

Current atherosclerosis reports - 1 Oct 2008

Iatan Iulia, Alrasadi Khalid, Ruel Isabelle, Alwaili Khalid, Genest Jacques

Abstract excerpt

The adenosine triphosphate-binding cassette A1 (ABCA1) gene codes for a cellular phospholipid and cholesterol transporter that mediates the initial and essential step in high-density lipoprotein (HDL) biogenesis: the formation of nascent HDL particles. Mutations at the ABCA1 gene locus cause severe familial HDL deficiency and, in the homozygous form, cause Tangier disease. Several studies have investigated the...

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Source

Identifiers

PMID: 18706283
DOI: 10.1007/s11883-008-0064-5

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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