Article
Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia--a comparative study of four differently designed, high resolution microarray platforms.
Genes, chromosomes & cancer - 1 Aug 2008
Gunnarsson Rebeqa, Staaf Johan, Jansson Mattias, Ottesen Anne Marie, Göransson Hanna, Liljedahl Ulrika, Ralfkiaer Ulrik, Mansouri Mahmoud, Buhl Anne Mette, Smedby Karin Ekström, Hjalgrim Henrik, Syvänen Ann-Christine, Borg Ake, Isaksson Anders, Jurlander Jesper, Juliusson Gunnar, Rosenquist Richard
Abstract excerpt
Screening for gene copy-number alterations (CNAs) has improved by applying genome-wide microarrays, where SNP arrays also allow analysis of loss of heterozygozity (LOH). We here analyzed 10 chronic lymphocytic leukemia (CLL) samples using four different high-resolution platforms: BAC arrays (32K)...
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