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Article

RNA interference by short hairpin RNAs expressed in vertebrate cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2004

Hannon Gregory J, Conklin Douglas S

Abstract excerpt

RNA interference (RNAi) is now established as a general method to silence gene expression in a variety of organisms. Double-stranded RNA (dsRNA), when introduced to cells, interferes with the expression of homologous genes, disrupting their normal function. In mammals, transient delivery of synthetic short interfering RNAs (siRNAs), which resemble the processed form of standard double stranded RNAi triggers, is...

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Identifiers

PMID: 14770011
DOI: 10.1385/1-59259-750-5:255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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