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Article

Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA.

Cell cycle (Georgetown, Tex.) - 1 Jan 2000

Scherr Michaela, Battmer Karin, Ganser Arnold, Eder Matthias

Abstract excerpt

RNA interference (RNAi) mediates sequence-specific posttranscriptional gene silencing triggered by double-stranded RNA. RNAi is an effective tool for functional genomics in C. elegans, whereas biochemical characteristics of RNAi hamper its use in mammalian cells. We here analyze kinetic and quantitative aspects of mammalian RNAi in different cell lines using novel lentiviral constructs with double H1-shRNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12734435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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