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Article

Ceramidase expression facilitates membrane turnover and endocytosis of rhodopsin in photoreceptors.

Proceedings of the National Academy of Sciences of the United States of America - 17 Feb 2004

Acharya Usha, Mowen Michael Beth, Nagashima Kunio, Acharya Jairaj K

Abstract excerpt

Transgenic expression of ceramidase suppresses retinal degeneration in Drosophila arrestin and phospholipase C mutants. Here, we show that expression of ceramidase facilitates the dissolution of incompletely formed and inappropriately located elements of rhabdomeric membranes in ninaE(I17) mutants lacking the G protein receptor Rh1 in R1-R6 photoreceptor cells. Ceramidase expression facilitates the endocytic...

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Identifiers

PMID: 14769922
DOI: 10.1073/pnas.0308693100
PMCID: PMC357028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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