Article
The Gos28 SNARE protein mediates intra-Golgi transport of rhodopsin and is required for photoreceptor survival.
The Journal of biological chemistry - 21 Nov 2014
Rosenbaum Erica E, Vasiljevic Eva, Cleland Spencer C, Flores Carlos, Colley Nansi Jo
Abstract excerpt
SNARE proteins play indispensable roles in membrane fusion events in many cellular processes, including synaptic transmission and protein trafficking. Here, we characterize the Golgi SNARE protein, Gos28, and its role in rhodopsin (Rh1) transport through Drosophila photoreceptors. Mutations in gos28 lead to defective Rh1 trafficking and retinal degeneration. We have pinpointed a role for Gos28 in the intra-Golgi...
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