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Article

Rhodopsin homeostasis and retinal degeneration: lessons from the fly.

Trends in neurosciences - 1 Nov 2013

Xiong Bo, Bellen Hugo J

Abstract excerpt

Rhodopsins (Rh) are G protein-coupled receptors that function as light-sensors in photoreceptors. In humans, Rh mutations cause retinitis pigmentosa (RP), a degenerative disease that ultimately results in blindness. Studies in Drosophila have provided many insights into basic Rh biology and have identified pathways that lead to retinal degeneration. It has been shown that, because Rh is very abundant in...

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Identifiers

PMID: 24012059
DOI: 10.1016/j.tins.2013.08.003
PMCID: PMC3955215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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