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Article

C/EBP is an essential component of PDGFRA transcription in MG-63 cells.

Biochemical and biophysical research communications - 5 Mar 2004

Afink Gijs, Westermark Ulrica K, Lammerts Ellen, Nistér Monica

Abstract excerpt

Interleukin-1beta (IL-1beta) is a potent inhibitor of platelet-derived growth factor alpha receptor (PDGFRalpha) expression in MG-63 cells. Its effect is mediated at the transcriptional level, but the transcription factors involved in this process are unknown. In the current study, we found that IL-1beta could inhibit the PDGFRalpha gene promoter activity, and this effect was strongly correlated with increased...

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Source

Identifiers

PMID: 14766209
DOI: 10.1016/j.bbrc.2004.01.056

Genes

EBP
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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