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Article

Interconnection of competence, stress and CiaR regulons in Streptococcus pneumoniae: competence triggers stationary phase autolysis of ciaR mutant cells.

Molecular microbiology - 1 Feb 2004

Dagkessamanskaia Adilia, Moscoso Miriam, Hénard Vincent, Guiral Sébastien, Overweg Karin, Reuter Mark, Martin Bernard, Wells Jerry, Claverys Jean-Pierre

Abstract excerpt

Of the 13 two-component signal transduction systems (TCS) identified in Streptococcus pneumoniae, two, ComDE and CiaRH, are known to affect competence for natural genetic transformation. ComD and ComE act together with the comC-encoded competence-stimulating peptide (CSP) and with ComAB, the CSP-dedicated exporter, to co-ordinate activation of genes required for differentiation to competence. Several lines of...

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PMID: 14763981
DOI: 10.1111/j.1365-2958.2003.03892.x

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