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Article

Exit from competence for genetic transformation in Streptococcus pneumoniae is regulated at multiple levels.

PloS one - 1 Jan 2013

Weng Liming, Piotrowski Andrew, Morrison Donald A

Abstract excerpt

Development of natural competence in S. pneumoniae entails coordinated expression of two sets of genes. Early gene expression depends on ComE, a response regulator activated by the pheromone CSP (Competence-Stimulating-Peptide). Subsequently, an early gene product (the alternative sigma factor ComX) activates expression of late genes, establishing the competent state. Expression of both sets of genes is...

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Identifiers

PMID: 23717566
DOI: 10.1371/journal.pone.0064197
PMCID: PMC3661451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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