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Article

Genome-Wide Screens Reveal New Gene Products That Influence Genetic Competence in Streptococcus mutans.

Journal of bacteriology - 15 Jan 2018

Shields Robert C, O'Brien Greg, Maricic Natalie, Kesterson Alexandria, Grace Megan, Hagen Stephen J, Burne Robert A

Abstract excerpt

A network of genes and at least two peptide signaling molecules tightly control when Streptococcus mutans becomes competent to take up DNA from its environment. Widespread changes in the expression of genes occur when S. mutans is presented with competence signal peptides in vitro, including the increased production of the alternative sigma factor, ComX, which activates late competence genes. Still, the way that...

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Identifiers

PMID: 29109185
DOI: 10.1128/JB.00508-17
PMCID: PMC5738738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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