Article
Gene expression analysis of the Streptococcus pneumoniae competence regulons by use of DNA microarrays.
Journal of bacteriology - 1 Nov 2000
Peterson S, Cline R T, Tettelin H, Sharov V, Morrison D A
Abstract excerpt
Competence for genetic transformation in Streptococcus pneumoniae is coordinated by the competence-stimulating peptide (CSP), which induces a sudden and transient appearance of competence during exponential growth in vitro. Models of this quorum-sensing mechanism have proposed sequential expression of several regulatory genes followed by induction of target genes encoding DNA-processing-pathway proteins. Although...
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