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Article

Transformation in Streptococcus pneumoniae: mosaic genes and the regulation of competence.

Research in microbiology - 1 Jan 2000

Hakenbeck R

Abstract excerpt

The presence of highly divergent mosaic blocks in penicillin binding protein genes responsible for penicillin resistance in Streptococcus pneumoniae implies that transformation is an important tool for the evolution of this pathogen. Genetic competence depends on production of the competence signaling peptide CSP, the processed product of comC, which is curiously part of a mosaic gene arrangement itself....

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PMID: 10961458
DOI: 10.1016/s0923-2508(00)00170-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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