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Article

The ciaR/ciaH regulatory network of Streptococcus pneumoniae.

Journal of molecular microbiology and biotechnology - 1 May 2002

Zähner Dorothea, Kaminski Kristina, van der Linden Mark, Mascher Thorsten, Meral Michelle, Hakenbeck Regine

Abstract excerpt

New mechanisms for beta-lactam resistance independent on the target penicillin-binding proteins were detected in beta-lactam-resistant laboratory mutants of Streptococcus pneumoniae. The link between mutations in the histidine protein kinase CiaH and phenotypic expression of cefotaxime resistance suggests that the cell is able to monitor the integrity of the cell wall and in emergency cases such as during the...

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PMID: 11931549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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