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Article

MYC is amplified in BRCA1-associated breast cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jan 2004

Grushko Tatyana A, Dignam James J, Das Soma, Blackwood Anne M, Perou Charles M, Ridderstråle Karin K, Anderson Kristin N, Wei Min-Jie, Adams April J, Hagos Fitsum G, Sveen Lise, Lynch Henry T, Weber Barbara L, Olopade Olufunmilayo I

Abstract excerpt

PURPOSE: Germ-line mutations in the BRCA1 tumor suppressor gene predispose to early onset breast cancers with a distinct phenotype characterized by high tumor grade, aneuploidy, high proliferation rate, and estrogen receptor-negativity. The molecular mechanisms and cooperative oncogenes contribut...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-myc

Source

Identifiers

PMID: 14760071
DOI: 10.1158/1078-0432.ccr-0976-03

Genes

BRCA1
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14760071-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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