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MYC and Breast Cancer

1 Jun 2010

Abstract excerpt

MYC is a key regulator of cell growth, proliferation, metabolism, differentiation, and apoptosis. MYC deregulation contributes to breast cancer development and progression and is associated with poor outcomes. Multiple mechanisms are involved in MYC deregulation in breast cancer, including gene amplification, transcriptional regulation, and mRNA and protein stabilization, which correlate with loss of tumor...

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PMID: 21779462
DOI: 10.1177/1947601910378691

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