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Article

Characteristics of MYC Amplification and Their Association with Clinicopathological and Molecular Factors in Patients with Breast Cancer.

DNA and cell biology - 1 May 2022

Cao Li, Ren Chongyang, Zhang Guochun, Li Xuerui, Chen Bo, Li Kai, Li Cheukfai, Mok Hsiaopei, Wang Yulei, Wen Lingzhu, Jia Minghan, Wei Guangnan, Lin Jiali, Liao Ning

Abstract excerpt

MYC amplification is detected in ∼15% of breast tumors and is associated with poor prognosis by mediating acquired resistance to anticancer therapies. This study aimed to determine the prevalence of MYC amplifications in Chinese women with breast cancer (BRCA) and investigate the correlation between MYC amplification and clinicopathological and molecular characteristics and its clinical implications. We analyzed...

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Identifiers

PMID: 35475703
DOI: 10.1089/dna.2020.6487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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