Article
c-MYC is a radiosensitive locus in human breast cells.
Oncogene - 17 Sept 2015
Wade M A, Sunter N J, Fordham S E, Long A, Masic D, Russell L J, Harrison C J, Rand V, Elstob C, Bown N, Rowe D, Lowe C, Cuthbert G, Bennett S, Crosier S, Bacon C M, Onel K, Scott K, Scott D, Travis L B, May F E B, Allan J M
Abstract excerpt
Ionising radiation is a potent human carcinogen. Epidemiological studies have shown that adolescent and young women are at increased risk of developing breast cancer following exposure to ionising radiation compared with older women, and that risk is dose-dependent. Although it is well understood which individuals are at risk of radiation-induced breast carcinogenesis, the molecular genetic mechanisms that...
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