Article
ERBB2, TBX2, RPS6KB1, and MYC alterations in breast tissues of BRCA1 and BRCA2 mutation carriers.
Genes, chromosomes & cancer - 1 Sept 2004
Adem Camilo, Soderberg Cheryl L, Hafner Kari, Reynolds Carol, Slezak Jeffrey M, Sinclair Colleen S, Sellers Thomas A, Schaid Daniel J, Couch Fergus, Hartmann Lynn C, Jenkins Robert B
Abstract excerpt
Breast cancer risk is greatly increased in women who carry mutations in the BRCA1 or BRCA2 genes. Because breast cancer initiation is different between BRCA1/2 mutation carriers and women who do not carry mutations, it is possible that the mechanism of breast cancer progression is also different. Histopathologic and genetic studies have supported this hypothesis. To test this hypothesis further, we utilized a...
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