Article
Breast tumor immunophenotype of BRCA1-mutation carriers is influenced by age at diagnosis.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2001
Vaziri S A, Krumroy L M, Elson P, Budd G T, Darlington G, Myles J, Tubbs R R, Casey G
Abstract excerpt
PURPOSE: Breast tumors of BRCA1 mutation carriers and those of early onset breast cancer cases share similar histological features, being generally high-grade, highly proliferative, aneuploid tumors that are predominantly estrogen- and progesterone-receptor negative. Because histological features of tumors of premenopausal women differ from those of tumors of older women, we sought to determine whether the...
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