Breast tumor immunophenotype of BRCA1-mutation carriers is influenced by age at diagnosis.

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Article

Breast tumor immunophenotype of BRCA1-mutation carriers is influenced by age at diagnosis.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2001

Vaziri S A, Krumroy L M, Elson P, Budd G T, Darlington G, Myles J, Tubbs R R, Casey G

Abstract excerpt

PURPOSE: Breast tumors of BRCA1 mutation carriers and those of early onset breast cancer cases share similar histological features, being generally high-grade, highly proliferative, aneuploid tumors that are predominantly estrogen- and progesterone-receptor negative. Because histological features...

Topics

Adult
Age of Onset
Aged
Aged, 80 and over
BRCA1 Protein
Breast Neoplasms
Cyclin D1
Cyclin E
Cytoskeletal Proteins
DNA Mutational Analysis
DNA, Neoplasm
Family Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Heterozygote

Humans

Immunohistochemistry

Ki-67 Antigen

Middle Aged

Source

Open in PubMed

Identifiers

PMID: 11448907

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-11448907-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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