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Article

The "CholesteROR" protective pathway in the vascular system.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2004

Boukhtouche Fatiha, Mariani Jean, Tedgui Alain

Abstract excerpt

Retinoic acid receptor-related Orphan Receptor alpha (RORalpha) is a member of the nuclear hormone receptor superfamily. RORalpha has long been considered as a constitutive activator of transcription in the absence of exogenous ligand; however, cholesterol has recently been identified as a natural ligand of RORalpha. The spontaneous staggerer (sg/sg) mutation is a deletion in the Rora gene that prevents the...

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Identifiers

PMID: 14751813
DOI: 10.1161/01.ATV.0000119355.56036.de

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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