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Article

Cerebellar purkinje cell loss in heterozygous rora+/- mice: a longitudinal study.

Journal of neurogenetics - 1 Jan 2000

Doulazmi Mohamed, Capone Francesca, Frederic Florence, Bakouche Joëlle, Boukhtouche Joëlle, Lemaigre-Dubreuil Yolande, Mariani Jean

Abstract excerpt

The staggerer (sg) mutation is a spontaneous deletion in the Rora gene that prevents the translation of the ligand-binding domain (LBD), leading to the loss of RORalpha activity. The homozygous Rorasg/sg mutant mouse, whose most obvious phenotype is ataxia associated with cerebellar degeneration, also displays a variety of other phenotypes. The heterozygous Rora+/sg is able to develop a cerebellum that is...

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PMID: 16807193
DOI: 10.1080/01677060600685832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Cerebellar purkinje cell loss in heterozygous rora+/- mice: a longitudinal study.PMID 16807193Read ↗

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