Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation of the hedgehog pathway in advanced prostate cancer

1 Jan 2004

Abstract excerpt

The hedgehog pathway plays a critical role in the development of prostate. However, the role of the hedgehog pathway in prostate cancer is not clear. Prostate cancer is the second most prevalent cause of cancer death in American men. Therefore, identification of novel therapeutic targets for prostate cancer has significant clinical implications. Here we report that activation of the hedgehog pathway occurs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hedgehog Signaling Pathway Studies
Share to Prostate Cancer Treatment and Research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 14749473
DOI: 10.1186/1476-4598-3-29

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation of the hedgehog pathway in advanced prostate cancerPMID 14749473Read ↗

Hedgehog pathway activity in the LADY prostate tumor modelSemantic proximity Read ↗

A mouse prostate cancer model induced by Hedgehog overexpression.Semantic proximity Read ↗

Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomasSemantic proximity Read ↗

Combination of hedgehog signaling blockage and chemotherapy leads to tumor reduction in pancreatic adenocarcinomas.Semantic proximity Read ↗

Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.Semantic proximity Read ↗

Role of GLI2 transcription factor in growth and tumorigenicity of prostate cells.Semantic proximity Read ↗

Hedgehog signaling is active in human prostate cancer stroma and regulates proliferation and differentiation of adjacent epitheliumSemantic proximity Read ↗

Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathwaySemantic proximity Read ↗

Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancerSemantic proximity Read ↗

Hedgehog signaling pathway as a therapeutic target in various types of cancer.Semantic proximity Read ↗

Unraveling the therapeutic potential of the Hedgehog pathway in cancer.Semantic proximity Read ↗

Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.