Article
Dnmt1 expression in pre- and postimplantation embryogenesis and the maintenance of IAP silencing.
Molecular and cellular biology - 1 Feb 2004
Gaudet F, Rideout W M, Meissner A, Dausman J, Leonhardt H, Jaenisch R
Abstract excerpt
The methylation of intracisternal A-type particle (IAP) sequences is maintained during mouse embryogenesis. Methylation suppresses IAP expression and the potential for mutagenesis by retrotransposition, but it is not clear how methylation of these elements is maintained during the embryonic stage...
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