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Examination of candidate chromosomal regions for type 2 diabetes reveals a susceptibility locus on human chromosome 8p23.1.

Diabetes - 1 Feb 2004

Pezzolesi Marcus G, Nam Moonsuk, Nagase Terumasa, Klupa Tomasz, Dunn Jonathon S, Mlynarski Wojciech M, Rich Stephen S, Warram James H, Krolewski Andrzej S

Abstract excerpt

In a panel of large Caucasian pedigrees, we genotyped markers in eight chromosomal regions previously reported as supporting linkage with type 2 diabetes. We previously reported significant linkage on chromosome 20q (maximum logarithm of odds score [MLS] = 2.79) in this panel. In the present analysis, candidate regions on 1q, 2q, 3q, 5q, 9q, and 10q yielded little evidence for linkage; a region on 2p (MLS = 1.64,...

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Identifiers

PMID: 14747302
DOI: 10.2337/diabetes.53.2.486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Examination of candidate chromosomal regions for type 2 diabetes reveals a susceptibility locus on human chromosome 8p23.1.PMID 14747302Read ↗

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