Article
Linkage but not association of calpain-10 to type 2 diabetes replicated in northern Sweden.
Diabetes - 1 Jun 2006
Einarsdottir Elisabet, Mayans Sofia, Ruikka Karin, Escher Stefan A, Lindgren Petter, Agren Asa, Eliasson Mats, Holmberg Dan
Abstract excerpt
We present data from a genome-wide scan identifying genetic factors conferring susceptibility to type 2 diabetes. The linkage analysis was based on 59 families from northern Sweden, consisting of a total of 129 cases of type 2 diabetes and 19 individuals with impaired glucose tolerance. Model-free linkage analysis revealed a maximum multipoint logarithm of odds score of 3.19 for D2S2987 at 267.7 cM (P=0.00058),...
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