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A genome scan for type 2 diabetes susceptibility loci in a genetically isolated population.

Diabetes - 1 Mar 2001

Permutt M A, Wasson J C, Suarez B K, Lin J, Thomas J, Meyer J, Lewitzky S, Rennich J S, Parker A, DuPrat L, Maruti S, Chayen S, Glaser B

Abstract excerpt

A total of 896 individuals of Ashkenazi Jewish descent were ascertained in Israel from 267 multiplex families, including 472 sib-pairs affected with type 2 diabetes. A genome-wide scan with average marker spacing of 9.5 cM revealed five regions on four chromosomes (4q, 8q, 14q, and 20q) that exhibited nominal evidence for linkage (P < 0.05). The highest observed nonparametric linkage Z score was 2.41 (equivalent...

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PMID: 11246891
DOI: 10.2337/diabetes.50.3.681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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