Article
A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus.
Nature genetics - 1 Jul 1998
Concannon P, Gogolin-Ewens K J, Hinds D A, Wapelhorst B, Morrison V A, Stirling B, Mitra M, Farmer J, Williams S R, Cox N J, Bell G I, Risch N, Spielman R S
Abstract excerpt
During the past decade, the genetics of type 1 (insulin-dependent) diabetes mellitus (IDDM) has been studied extensively and the disorder has become a paradigm for genetically complex diseases. Previous genome screens and studies focused on candidate genes have provided evidence for genetic linkage between polymorphic DNA markers and 15 putative IDDM susceptibility loci, designated IDDM1-IDDM15. We have carried...
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