Article
Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans.
American journal of human genetics - 1 Apr 1999
Duggirala R, Blangero J, Almasy L, Dyer T D, Williams K L, Leach R J, O'Connell P, Stern M P
Abstract excerpt
Since little is known about chromosomal locations harboring type 2 diabetes-susceptibility genes, we conducted a genomewide scan for such genes in a Mexican American population. We used data from 27 low-income extended Mexican American pedigrees consisting of 440 individuals for whom genotypic data are available for 379 markers. We used a variance-components technique to conduct multipoint linkage analyses for...
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