The search for type 2 diabetes susceptibility loci: the chromosome 1q story.

doi:10.1007/s11892-007-0025-3

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Article

The search for type 2 diabetes susceptibility loci: the chromosome 1q story.

Current diabetes reports - 1 Apr 2007

Das Swapan Kumar, Elbein Steven C

Abstract excerpt

The unbiased approach of genome-wide linkage analysis has shown evidence for linkage of type 2 diabetes mellitus to the chromosome 1q21-25 region in at least eight independent studies. More than 26 candidate genes have already been evaluated, but to date none explain the evidence for linkage in this gene-dense region. Considerable data suggest that multiple genes account for this linkage result. The search for...

Topics

Animals
Chromosomes, Human, Pair 1
Computational Biology
Diabetes Mellitus, Type 2
Genetic Linkage
Genetic Predisposition to Disease
Humans
International Cooperation

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Open in PubMed

Identifiers

PMID: 17425920
DOI: 10.1007/s11892-007-0025-3

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