Article
Apoptosis-related gene expression after hyperthermia in human tongue squamous cell carcinoma cells harboring wild-type or mutated-type p53.
Cancer letters - 10 Feb 2004
Yasumoto Jun-ichi, Kirita Tadaaki, Takahashi Akihisa, Ohnishi Ken, Imai Yuichiro, Yuki Kazue, Ohnishi Takeo
Abstract excerpt
Hyperthermia is useful for the treatment of human head and neck cancer, as it is relatively easy to perform thermoregulation when compared with deep organs. In this study, we focused attention on the p53 as a predictive indicator of hyperthermic cancer therapy. We used two kinds of cell lines of a human squamous cell carcinoma (SAS) with identical backgrounds of function except for the p53 protein. We assayed the...
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