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Article

Mild hyperthermia-induced apoptosis is dependent on p53 in human lymphoid cells.

Research communications in molecular pathology and pharmacology - 1 Jan 1999

Seo Y R, Smith M L, Han S S, Fairbairn D W, O'Neill K L, Ryu J C

Abstract excerpt

Mild hyperthermia is known to enhance apoptosis. The p53 tumor-suppressor gene product has been shown to function in apoptosis in response to genotoxic stress. However, there is little information regarding the mechanism of p53-dependent apoptosis induced by heat stress. In present study, a p53 contribution in mild hyperthermia-induced apoptosis was investigated in human lymphoid system. After 30-minute exposure...

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PMID: 10741379

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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