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Article

Analysis of apoptosis-related gene expression after X-ray irradiation in human tongue squamous cell carcinoma cells harboring wild-type or mutated p53 gene.

Journal of radiation research - 1 Mar 2003

Yasumoto Junichi, Imai Yuichiro, Takahashi Akihisa, Ohnishi Ken, Yuki Kazue, Kirita Tadaaki, Ohnishi Takeo

Abstract excerpt

Mutations in the p53 tumor suppressor gene have recently been reported to have an impact on clinical trials of several human tumors, including head and neck cancers. To confirm the p53-dependence of X-ray induced apoptosis, we used two cell lines derived from a human squamous cell carcinoma (SAS) with identical genetic backgrounds, except for the p53 gene, which are SAS/mp53 cells with mp53 and SAS/neo cells with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12841598
DOI: 10.1269/jrr.44.41

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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