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Article

Hyperthermia induces translocation of apoptosis-inducing factor (AIF) and apoptosis in human glioma cell lines.

Journal of neuro-oncology - 1 Dec 2004

Fukami Tadateru, Nakasu Satoshi, Baba Kazumi, Nakajima Masayuki, Matsuda Masayuki

Abstract excerpt

In the hyperthermal treatment, the wild type (wt) p53 plays an important role in apoptosis induction in the tumor cells. In human gliomas, p53 frequently has some form of mutation. The mutant type (mt) p53 does not work properly as a tumor suppressor and this may result in poor responses during treatment. We investigated the relationship between apoptosis-inducing factor (AIF) and apoptosis under various thermal...

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Identifiers

PMID: 15662973
DOI: 10.1007/s11060-004-9168-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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