Article
Risperidone response and 5-HT6 receptor gene variance: genetic association analysis with adjustment for nongenetic confounders.
Schizophrenia research - 1 Mar 2004
Lane Hsien-Yuan, Lin Cheng-Chieh, Huang Chiung-Hsien, Chang Yue-Cune, Hsu Shih-Kuan, Chang Wen-Ho
Abstract excerpt
Previous genetic-response studies, usually without considering environmental factors, encountered great difficulties in replication of results. Although atypical antipsychotics are becoming the mainstay for schizophrenia treatment which makes an antipsychotic "atypical" remains unclear. Risperidone (a widely used atypical antipsychotic agent) and several other atypicals have high affinities for 5-HT6 and 5-HT7...
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