Article
Association study of serotonin-6 receptor variant (C267T) with schizophrenia and aggressive behavior.
Neuroscience letters - 20 Aug 1999
Tsai S J, Chiu H J, Wang Y C, Hong C J
Abstract excerpt
The relative abundance of serotonin type 6 receptors (5-HT6) in some limbic regions and the high affinity of some antipsychotics to 5-HT6 receptors suggest that they might be involved in the pathogenesis of schizophrenic disorders. In a population-based association study, we tested the hypothesis that the allelic variant, C267T, of the human 5-HT6 gene confers susceptibility to schizophrenic disorders and...
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