Association study of serotonin-6 receptor variant (C267T) with schizophrenia and aggressive behavior.

doi:10.1016/s0304-3940(99)00542-x

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Article

Association study of serotonin-6 receptor variant (C267T) with schizophrenia and aggressive behavior.

Neuroscience letters - 20 Aug 1999

Tsai S J, Chiu H J, Wang Y C, Hong C J

Abstract excerpt

The relative abundance of serotonin type 6 receptors (5-HT6) in some limbic regions and the high affinity of some antipsychotics to 5-HT6 receptors suggest that they might be involved in the pathogenesis of schizophrenic disorders. In a population-based association study, we tested the hypothesis that the allelic variant, C267T, of the human 5-HT6 gene confers susceptibility to schizophrenic disorders and...

Topics

Adult
Age Factors
Aggression
Agonistic Behavior
Alleles
Female
Genotype
Humans
Male
Polymorphism, Genetic
Protein Isoforms
Receptors, Serotonin
Sex Factors

Source

Open in PubMed

Identifiers

PMID: 10477121
DOI: 10.1016/s0304-3940(99)00542-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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