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Article

Novel polymorphism in the 5'-upstream region of the human 5-HT6 receptor gene and schizophrenia.

Neuroscience letters - 7 Sept 2001

Ohmori O, Shinkai T, Hori H, Nakamura J

Abstract excerpt

The localization of 5-hydroxytryptamine6 (5-HT6) receptor in the limbic and cortical regions, and the high affinity of atypical antipsychotic drugs such as clozapine for the receptor, suggest the possible involvement of the receptor in the pathogenesis of schizophrenia. In this study, we searched systematically for polymorphisms in the 5'-upstream region of the human 5-HT6 receptor gene. We identified a...

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Identifiers

PMID: 11524147
DOI: 10.1016/s0304-3940(01)02075-4

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