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Genetic variants in the BDNF gene and therapeutic response to risperidone in schizophrenia patients: a pharmacogenetic study.

European journal of human genetics : EJHG - 1 Jun 2010

Xu Mingqing, Li Sheng, Xing Qinghe, Gao Rui, Feng Guoyin, Lin Zhiguang, St Clair David, He Lin

Abstract excerpt

Risperidone is a widely used atypical antipsychotic agent that produces considerable interindividual differences in patient response. We investigated the pharmacogenetic relationship between the brain-derived neurotrophic factor (BDNF) gene and response to risperidone in 127 Han Chinese schizophrenic patients. Three functional polymorphisms, (GT)(n) dinucleotide repeat polymorphism, C-270T, and the rs6265G/A...

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Antipsychotic Agents
Biomarkers, Pharmacological
Brain-Derived Neurotrophic Factor
China
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pharmacogenetics

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PMID: 20087404
DOI: 10.1038/ejhg.2009.238
PMCID: PMC2987331

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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