Article
Dopamine transporter polymorphisms and risperidone response in Chinese schizophrenia patients: an association study.
Pharmacogenomics - 1 Oct 2007
Zhang Aiping, Xing Qinghe, Wang Lei, Du Jing, Yu Lan, Lin Zhiguang, Li Xingwang, Feng Guoyin, He Lin
Abstract excerpt
Risperidone is a widely used atypical antipsychotic medication and there is currently considerable interest in individual differences in patient response to it. In this study, we investigated the pharmacogenetic correlates of SLC6A3 and response to risperidone treatment in 130 Chinese schizophrenia patients. We selected six polymorphisms, including two SNPs in the 5'-regulatory regions, two SNPs in intron 1, one...
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