Article
Thioglycosynthases: double mutant glycosidases that serve as scaffolds for thioglycoside synthesis.
Chemical communications (Cambridge, England) - 7 Feb 2004
Jahn Michael, Chen Hongming, Müllegger Johannes, Marles Jennifer, Warren R Antony J, Withers Stephen G
Abstract excerpt
A double mutant, retaining glycosidase that lacks both the catalytic nucleophile and the catalytic acid/base residues efficiently catalyzes thioglycoside formation from a glycosyl fluoride donor and thiosugar acceptors.
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