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Article

Structural basis for transglycosylation in glycoside hydrolase family GH116 glycosynthases.

Archives of biochemistry and biophysics - 30 Jul 2021

Pengthaisong Salila, Hua Yanling, Ketudat Cairns James R

Abstract excerpt

Glycosynthases are glycoside hydrolase mutants that can synthesize oligosaccharides or glycosides from an inverted donor without hydrolysis of the products. Although glycosynthases have been characterized from a variety of glycoside hydrolase (GH) families, family GH116 glycosynthases have yet to be reported. We produced the Thermoanaerobacterium xylanolyticum TxGH116 nucleophile mutants E441D, E441G, E441Q and...

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Identifiers

PMID: 34019851
DOI: 10.1016/j.abb.2021.108924

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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