Article
Co-existence of risk and protective haplotypes of Calpain 10 gene to type 2 diabetes in the eastern Indian population.
Diabetes & vascular disease research - 1 Jan 2010
Adak Sangeeta, Sengupta Sanghamitra, Chowdhury Subhankar, Bhattacharyya Maitree
Abstract excerpt
Linkage and association studies have detected a role for Calpain-10 (CAPN10) polymorphisms in susceptibility to T2DM in many populations. This study aimed to evaluate possible associations between three SNPs in the CAPN10 (UCSNPs -43, -19 and -63) gene and T2DM in the east Indian population. The distribution of genotype frequency of UCSNP-63 varied significantly between T2DM patients and controls under a dominant...
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