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Article

Calpain 10 and type 2 diabetes: are we getting closer to an explanation?

Current opinion in clinical nutrition and metabolic care - 1 Jul 2005

Ridderstråle Martin, Parikh Hemang, Groop Leif

Abstract excerpt

PURPOSE OF REVIEW: A variation in the gene encoding the cysteine protease calpain 10 (CAPN10) was recently linked and associated with type 2 diabetes by positional cloning. This positional cloning was a follow-up investigation to the identification of a diabetes-linked region on human chromosome 2 identified by genome-wide scanning a few years earlier. In this paper we give a general background on the genetic...

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Share to Calpain
Share to Chromosomes, Human, Pair 2
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to CAPN10 gene

Share to Genetic Predisposition to Disease

Share to Haplotypes

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 15930958
DOI: 10.1097/01.mco.0000172573.25902.33

Genes

CAPN10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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