Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Yeast N-glycanase distinguishes between native and non-native glycoproteins.

EMBO reports - 1 Feb 2004

Hirsch Christian, Misaghi Shahram, Blom Daniël, Pacold Michael E, Ploegh Hidde L

Abstract excerpt

N-glycanase from Saccharomyces cerevisiae (Png1) preferentially removes N-glycans from misfolded proteins. The ability of Png1 to distinguish between folded and misfolded glycoproteins is reminiscent of substrate recognition by UDP-glucose glycoprotein glucosyl transferase, an enzyme that possess...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha 1-Antitrypsin
Share to Glycoproteins
Share to Glycoside Hydrolases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycosylation

Share to Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase

Share to Protein Folding

Share to Ribonucleases

Share to Substrate Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 14726951
DOI: 10.1038/sj.embor.7400066
PMCID: PMC1298977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14726951-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Yeast N-glycanase distinguishes between native and non-native glycoproteins.PMID 14726951Read ↗

PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase.Semantic proximity Read ↗

The cytoplasmic peptide:N-glycanase (NGLY1) - Structure, expression and cellular functions.Semantic proximity Read ↗

The role of UDP-Glc:glycoprotein glucosyltransferase 1 in the maturation of an obligate substrate prosaposin.Semantic proximity Read ↗

Structural Analysis of Free N-Glycans in α-Glucosidase Mutants of Saccharomyces cerevisiae: Lack of the Evidence for the Occurrence of Catabolic α-Glucosidase Acting on the N-Glycans.Semantic proximity Read ↗

ER-associated degradation relying on protein O-mannosylationSemantic proximity Read ↗

Cytoplasmic peptide:N-glycanase cleaves N-glycans on a carboxypeptidase Y mutant during ERAD in Saccharomyces cerevisiae.Semantic proximity Read ↗

A Complex of Htm1 and the Oxidoreductase Pdi1 Accelerates Degradation of Misfolded Glycoproteins.Semantic proximity Read ↗

UDP-glucose:glycoprotein glucosyltransferase (UGGT1) promotes substrate solubility in the endoplasmic reticulum.Semantic proximity Read ↗

Direct assay for endo-α-mannosidase substrate preference on correctly folded and misfolded model glycoproteins.Semantic proximity Read ↗

Metabolism of free oligosaccharides is facilitated in the och1Δ mutant of Saccharomyces cerevisiae.Semantic proximity Read ↗

Yeast GTB1 encodes a subunit of glucosidase II required for glycoprotein processing in the endoplasmic reticulum.Semantic proximity Read ↗

Endo-β-N-acetylglucosaminidase forms N-GlcNAc protein aggregates during ER-associated degradation in Ngly1-defective cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.