Article
Metabolism of free oligosaccharides is facilitated in the och1Δ mutant of Saccharomyces cerevisiae.
Glycobiology - 1 Oct 2011
Hirayama Hiroto, Suzuki Tadashi
Abstract excerpt
In eukaryotic cells, it is known that N-glycans play a pivotal role in quality control of carrier proteins. Although "free" forms of oligosaccharides (fOSs) are known to be accumulated in the cytosol, the precise mechanism of their formation, degradation and biological relevance remains poorly understood. It has been shown that, in budding yeast, almost all fOSs are formed from misfolded glycoproteins. Precise...
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